Fig. 6

USP13 regulated tumorigenesis of HCC cells via WWP1 in vivo. A The nude mice bearing tumors were euthanized and photographed. B Images of tumors from the nude mice in A. A ruler was used to indicate the size of tumors. C Tumor growth curves from the nude mice in A . D The nude mice bearing tumors were euthanized and photographed. E Images of tumors from the nude mice in D. A ruler was used to indicate the size of tumors. F Tumor growth curves from the nude mice in D . G, I IHC analysis of Ki67 expression in tumors shown in B and E. H, J Quantification and statistical analysis of the Ki67 IHC scores. K, L USP13 and WWP1 protein level in tumors from nude mice were detected by WB. Scale bars: 50 µm